The number 322 is most well known for it's association with the Yale fraternity Skull and Bones (Also, Scull and Bones). The 2004 elections held in the United States took place between two candidates, George W. Bush and John F. Kerry, both of whom were members of Skull and Bones.

According to Skull and Bones lore, in the year 322 B.C. a Greek orator died. When he died, the goddess Eulogia whom Skull and Bones called the goddess of eloquence, arose to the heavens and didn't return until 1832, where she took up residence in The Tomb of Skull and Bones. Skull and Bones does everything in deference to this goddess. They sing sacred anthems, and are encouraged to steal things, some remarkably valuable items, to bring back as gifts for the goddess. They begin each session in the tomb, and they meet twice weekly by unveiling a guilt shrine to Eulogia. They call themselves the Knights of Eulogia.

322 has many core numerological implications. The sum of its constituent parts is 7 (3+2+2). The number 7 is commonly used to divide full spectrums into compartments. Time is divided into 7 days of the week, light into 7 colors in a rainbow, octaves into 7 notes in a musical scale, and so on. The use of 7 may likely be derived from the number three, due to the following set: [1] [2] [3] [1,2] [1,3] [2,3] [1,2,3]

The Gregorian Calendar places the first day of the week at Sunday and the seventh day of the week at Saturday. Including the Sun, Saturn is the seventh planet in our solar system. In Roman mythology Saturn is the god of agriculture, founder of civilizations and of social order and conformity. Thus the number 7 and 322 may hold a saturnalian resonance.

Alternatively, the number 322 may be seen as 32x2. There are 32 white squares and 32 black squares on a chess board. 32/2 = 16 (4x4) and ties directly into the idea of squares. The equation 4x4 may be spoken as "Four Squared". There are four weeks per month in the Gregorian Calendar. 3x2x2 = 12 as in the number of months in a year, the number of colors on the color wheel, and the number of chromatic notes in a subdivided musical octave. The idea of 3 blooming into 7 into 12 is a teaching derived from Jewish mysticism called the Sephir Yetzirah.

The sum of the Sephir Yetzirah's parts are 22 (3+7+12). Thus we move from the central emanation point (a point without quantitative value) to the number 3 and out into the whole shape of 22 rays. 322 may be seen as a representation of the birthing process.